RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor with anticancer activity. RAMB4 inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites. RAMB4 triggers a ubiquitin-proteasome-system (UPS)-stress response without affecting 20S proteasome catalytic activities.
Molecular Weight:
413.12
Purity:
>98%
CAS Number:
[145888-79-5]
Formula:
C19H13Cl4NO
Target:
Proteasome
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