Voxelotor (GBT 440) is a first-in-class, potent polymeric inhibitor of sickle hemoglobin (HbS). Voxelotor (GBT440) binds to the N-terminal a chain of haemoglobin (Hb), increases haemoglobin S (HbS) affinity for oxygen, delays in vitro HbS polymerization and prevents sickling of red blood cells (RBCs).
Molecular Weight:
337.37
Purity:
>99%
CAS Number:
[1446321-46-5]
Formula:
C19H19N3O3
Target:
Others
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