Finerenone (BAY 94-8862) is a third generation selective, oral active, non-steroidal halocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone showed good selectivity (>500-fold) compared to glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (AR). Finerenone has potential applications in the study of heart and kidney diseases, such as type 2 diabetes and chronic kidney disease.
Molecular Weight:
378.43
Purity:
99.50%
CAS Number:
[1050477-31-0]
Formula:
C21H22N4O3
Target:
Mineralocorticoid Receptor
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