TRAF6 Antibody - middle region
Catalog Number:
ASB-ARP30226_P050
- Images (5)
| Article Name: | TRAF6 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP30226_P050 |
| Supplier Catalog Number: | ARP30226_P050 |
| Alternative Catalog Number: | ASB-ARP30226_P050-25UL,ASB-ARP30226_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human TRAF6 |
| Alternative Names: | RNF85, MGC:3310 |
| TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. |
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WB Suggested Anti-TRAF6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate |
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Host: Rabbit Target Name: TRAF6 Sample Type: Human Fetal Lung Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: TRAF6 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: TRAF6 Sample Type: Human Adult Placenta Antibody Dilution: 1.0ug/ml |
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TRAF6 antibody - middle region (ARP30226_P050) in Human 293T using Western Blot |
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