ARRB1 Antibody - middle region
Catalog Number:
ASB-ARP30523_P050
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| Article Name: | ARRB1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP30523_P050 |
| Supplier Catalog Number: | ARP30523_P050 |
| Alternative Catalog Number: | ASB-ARP30523_P050-25UL,ASB-ARP30523_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human ARRB1 |
| Alternative Names: | ARB1, ARR1 |
| Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. |
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