WNT1 Antibody - middle region
Catalog Number:
ASB-ARP32122_P050
- Images (5)
| Article Name: | WNT1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP32122_P050 |
| Supplier Catalog Number: | ARP32122_P050 |
| Alternative Catalog Number: | ASB-ARP32122_P050-25UL,ASB-ARP32122_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human WNT1 |
| Alternative Names: | INT1, OI15, BMND16 |
| WNT1 is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT1 is very conserved in evolution, and it is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. WNT1 was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. WNT1 is clustered with another family member, WNT10B, in the chromosome 12q13 region.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-WNT1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Muscle |
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Sample Type: 1. Molecular Weight 2. Control (20ug) 3. shRNA1-WNT1 H9 hES cells (20ug) 4.A,AshRNA2-WNT1 H9 hES cells (20ug) Primary Dilution: 1:1000 Secondary Antibody: anti-Rabbit HRP Secondary Dilution: 1:5000 Image Submitted By: Jingli Cai Thomas Jefferson UniversityA,A |
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Host: Rabbit Target Name: WNT1 Sample Tissue: Human HepG2 Antibody Dilution: 1.0ug/ml |
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Host: Mouse Target Name: WNT1 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml |
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WNT1 antibody - middle region (ARP32122_P050) in Human H9 using Western Blot |
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