ZUP1 Antibody - middle region, Rabbit, Polyclonal

Product Overview

• Article Name: ZUP1 Antibody - middle region, Rabbit, Polyclonal
• Biozol Catalog Number: ASB-ARP32274_P050
• Supplier Catalog Number: ARP32274_P050
• Alternative Catalog Number: ASB-ARP32274_P050-25UL,ASB-ARP32274_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C6orf113
• Alternative Names: DUB, ZUFSP, C6orf113

Product Description

This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 66kDa
• NCBI: 221302
• UniProt: Q96AP4
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.