NKX2-2 Antibody - N-terminal region

Product Overview

• Article Name: NKX2-2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP32338_P050
• Supplier Catalog Number: ARP32338_P050
• Alternative Catalog Number: ASB-ARP32338_P050-25UL,ASB-ARP32338_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NKX2-2
• Alternative Names: NKX2B, NKX2.2

Product Description

Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 30kDa
• NCBI: 4821
• UniProt: O95096
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Sample Type: Human Optic Nerve and Spinal CordCellular Target: Oligoden Drocyte Lineage CellsPrimary
Dilution: IHC-PZ 1:500, IHC-P 1:1000

WB Suggested Anti-NKX2-2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Spleen

Host: Mouse
Target Name: NKX2-2
Sample Tissue: Mouse Pancreas
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: NKX2-2
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 1ug/ml

NKX2-2 antibody - N-terminal region (ARP32338_P050) in Human Spleen using Western Blot