RUVBL1 Antibody - N-terminal region

Product Overview

• Article Name: RUVBL1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP32349_P050
• Supplier Catalog Number: ARP32349_P050
• Alternative Catalog Number: ASB-ARP32349_P050-25UL,ASB-ARP32349_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL1
• Alternative Names: RVB1, TIH1, ECP54, TIP49, ECP-54, INO80H, NMP238, PONTIN, TIP49A, NMP 238, Pontin52

Product Description

RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3 to 5) activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 50kDa
• NCBI: 8607
• UniProt: Q9Y265
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-RUVBL1 antibody
Catalog Number: ARP32349
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-RUVBL1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human heart

WB Suggested Anti-RUVBL1 Antibody
Positive Control: Lane 1: 30ug K562 lysate
Primary Antibody Dilution : 1:200
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:1000
Submitted by: Sustackova Gabriela

Host: Rabbit
Target Name: RUVBL1
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

RUVBL1 antibody - N-terminal region (ARP32349_P050) in Human Heart using Western Blot