PLP1 Antibody - middle region

Product Overview

• Article Name: PLP1 Antibody - middle region
• Biozol Catalog Number: ASB-ARP33844_P050
• Supplier Catalog Number: ARP33844_P050
• Alternative Catalog Number: ASB-ARP33844_P050-25UL,ASB-ARP33844_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLP1
• Alternative Names: PLP, PMD, HLD1, MMPL, SPG2, GPM6C, PLP/DM20

Product Description

PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5 UTRs, have been identified for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 30kDa
• NCBI: 5354
• UniProt: P60201
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-PLP1 antibody
Catalog Number: ARP33844
Formalin Fixed Paraffin Embedded Tissue: Human Brain, Cortex
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec

WB Suggested Anti-PLP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate

Host: Mouse
Target Name: PLP1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: PLP1
Positive control (+): Human Brain (BR)
Negative control (-): Human Fetal Heart (HE)
Antibody concentration: 1ug/ml

PLP1 antibody - middle region (ARP33844_P050) in Human HeLa using Western Blot