XRCC5 Antibody - C-terminal region

Product Overview

• Article Name: XRCC5 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP34121_T100
• Supplier Catalog Number: ARP34121_T100
• Alternative Catalog Number: ASB-ARP34121_T100-25UL,ASB-ARP34121_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human XRCC5
• Alternative Names: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1

Product Description

XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 83kDa
• NCBI: 7520
• UniProt: Q4VBQ5
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Pancreas

Sample Type:
Human lung adenocarcinoma cell line A549Primary Antibody Dilution:
1:100Secondary Antibody:
Goat anti-rabbit AlexaFluor 488Secondary Antibody Dilution:
1:400Color/Signal Descriptions:
XRCC5: Green DAPI:BlueGene Name:
XRCC5 Submitted by:
Dr. Crissy Dudgeon, Ph.D., CINJ

WB Suggested Anti-XRCC5 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysateXRCC5 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Lanes:
1. 30 ug MiaPaca-2 cell lysate
2. 30 ug Panc-1 cell lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Goat anti-Rabbit HRP
Secondary Antibody Dilution:
1:4000
Gene Name:
XRCC5
Submitted by:
Dr. Crissy Dudgeon, Ph.D., CINJ

XRCC5 antibody - C-terminal region (ARP34121_T100) in Human Jurkat using Western Blot