SIAH1 Antibody - N-terminal region

Product Overview

• Article Name: SIAH1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP34163_T100
• Supplier Catalog Number: ARP34163_T100
• Alternative Catalog Number: ASB-ARP34163_T100-25UL,ASB-ARP34163_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIAH1
• Alternative Names: SIAH1A

Product Description

SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinsons disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 35kDa
• NCBI: 6477
• UniProt: Q8IUQ4-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-SIAH1 antibody
Catalog Number: ARP34163_T100
Paraffin Embedded Tissue: Human Heart cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-SIAH1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate

Host: Mouse
Target Name: SIAH1A
Sample Tissue: Mouse Liver
Antibody Dilution: 1ug/ml

Researcher: Peter Brand & Dr. Oliver Kramer, Institute for Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University JenaApplication: Western blottingSpecies+tissue/cell type: Human embryonic kidney 293THow many uga€(TM)s of tissue/cell lysate run on the gel:1: 50 ug human HEK-293T cell lysatePrimary antibody dilution: 1:1000Secondary antibody: Anti-rabbit-IgGSecondary antibody dilution: 1:5000 - See more at: http://www.avivasysbio.com/anti-siah1-antibody-n-terminal-region-arp34163-t100.htmlsthash.GIS7dILc.dpufSIAH1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells

SIAH1 antibody - N-terminal region (ARP34163_T100) in Human Jurkat using Western Blot