KEAP1 Antibody - C-terminal region

Product Overview

• Article Name: KEAP1 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP34728_T100
• Supplier Catalog Number: ARP34728_T100
• Alternative Catalog Number: ASB-ARP34728_T100-25UL,ASB-ARP34728_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KEAP1
• Alternative Names: INrf2, KLHL19

Product Description

KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 70kDa
• NCBI: 9817
• UniProt: Q14145
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

WB Suggested Anti-KEAP1 Antibody Titration: 1.0ug/ml
Positive Control: HepG2 cell lysateKEAP1 is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: KEAP1
Sample Type: HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1.25ug/mL
Peptide Concentration: 1.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12%KEAP1 is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: KEAP1
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 1ug/ml

KEAP1 antibody - C-terminal region (ARP34728_T100) in Human HepG2 using Western Blot