CNBP Antibody - N-terminal region

Product Overview

• Article Name: CNBP Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP34815_P050
• Supplier Catalog Number: ARP34815_P050
• Alternative Catalog Number: ASB-ARP34815_P050-25UL,ASB-ARP34815_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Canine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNBP
• Alternative Names: DM2, ZNF9, CNBP1, PROMM, RNF163, ZCCHC22

Product Description

CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 19 kDa
• NCBI: 7555
• UniProt: P62633
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

CNBP antibody - N-terminal region (ARP34815_P050) validated by WB using human primary myoblasts at 1:1000.

WB Suggested Anti-CNBP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: Human brain

25 ug of the indicated Human whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.

Host: Rabbit
Target Name: CNBP
Sample Tissue: Human 293T Whole Cell
Antibody Dilution: 1ug/ml

CNBP antibody - N-terminal region (ARP34815_P050) in human primary myoblasts using Western Blot