VDAC1 Antibody - C-terminal region

Product Overview

• Article Name: VDAC1 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP35122_T100
• Supplier Catalog Number: ARP35122_T100
• Alternative Catalog Number: ASB-ARP35122_T100-25UL,ASB-ARP35122_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human VDAC1
• Alternative Names: PORIN, VDAC-1

Product Description

The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 31kDa
• NCBI: 7416
• UniProt: Q5FVE7
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-VDAC1 Antibody
Catalog Number: ARP35122
Paraffin Embedded Tissue: Human Liver
Cellular Data: Hepatocytes
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-VDAC1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysateVDAC1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells

Lanes:
Lane 1: 50ug HeLa lysate
Lane 2: 50ug 293T lysate
Lane 3: 50ug K562 lysate
Lane 4: 50ug MDA-MB-231 lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Gene Name:
VDAC1
Submitted by:
David Colecchia, Ph.D, Istituto Toscano Tumori, Core Research Laboratory, presso Fondazione Toscana Life Sciences

Host: Rabbit
Target: VDAC1
Positive control (+): Human Stomach Tumor (T-ST)
Negative control (-): Human Lung (LU)
Antibody concentration: 5ug/ml

VDAC1 antibody - C-terminal region (ARP35122_T100) in Human HepG2 using Western Blot