KCNH5 Antibody - N-terminal region

Catalog Number: ASB-ARP35478_P050
Article Name: KCNH5 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP35478_P050
Supplier Catalog Number: ARP35478_P050
Alternative Catalog Number: ASB-ARP35478_P050-25UL,ASB-ARP35478_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNH5
Alternative Names: EAG2, hEAG2, H-EAG2, Kv10.2
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 112 kDa
NCBI: 27133
UniProt: Q8NCM2-2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Brain
WB Suggested Anti-KCNH5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Recognizes isoform 2 at ~70 kDa in these samples which do not appear to express isoform 1 at 112 kDa.
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide sequence is present in an isoform at 69 kDa and a shorter isoform present at 48 kDa.
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