MAGEA9 Antibody - middle region
Catalog Number:
ASB-ARP35768_P050
- Images (0)
| Article Name: | MAGEA9 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP35768_P050 |
| Supplier Catalog Number: | ARP35768_P050 |
| Alternative Catalog Number: | ASB-ARP35768_P050-25UL,ASB-ARP35768_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Human, Porcine, Rabbit, Rat, Yeast |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human MAGEA9 |
| Alternative Names: | CT1.9, MAGE9 |
| MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. |
Product Guarantee and Expert Support
