L3MBTL Antibody - N-terminal region

Product Overview

• Article Name: L3MBTL Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP35895_P050
• Supplier Catalog Number: ARP35895_P050
• Alternative Catalog Number: ASB-ARP35895_P050-25UL,ASB-ARP35895_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL
• Alternative Names: L3MBTL, ZC2HC3, H-L(3)MBT, dJ138B7.3

Product Description

L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 86kDa
• NCBI: 26013
• UniProt: Q9Y468
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.