ATF3 Antibody - middle region
Catalog Number:
ASB-ARP36556_P050
- Images (6)
| Article Name: | ATF3 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP36556_P050 |
| Supplier Catalog Number: | ARP36556_P050 |
| Alternative Catalog Number: | ASB-ARP36556_P050-25UL,ASB-ARP36556_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human ATF3 |
| This protein binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. ATF3 represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. |
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Host: Rabbit Target Name: ATF3 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 1ug/ml |
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Host: Rabbit Target: ATF3 Positive control (+): Human liver (LI) Negative control (-): Stomach tumor (T-ST) Antibody concentration: 3ug/ml |
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WB Suggested Anti-ATF3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: OVCAR-3 cell lysate |
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Host: Rabbit Target Name: ATF3 Sample Type: OVCAR-3 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0.12 |
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Host: Rabbit Target Name: ATF3 Sample Tissue: Human 293T Antibody Dilution: 1.0ug/ml |
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ATF3 antibody - middle region (ARP36556_P050) in Human Jurkat Whole Cell using Western Blot |
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