GJC2 Antibody - middle region

Product Overview

• Article Name: GJC2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP36621_P050
• Supplier Catalog Number: ARP36621_P050
• Alternative Catalog Number: ASB-ARP36621_P050-25UL,ASB-ARP36621_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Human, Rabbit
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJC2
• Alternative Names: Cx47, HLD2, GJA12, SPG44, CX46.6, LMPH1C, LMPHM3, PMLDAR

Product Description

GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 47kDa
• NCBI: 57165
• UniProt: Q5T442
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-GJC2 Antibody
Catalog Number: ARP36621_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult heart
Observed Staining: Membrane, some cytoplasm
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Protocol located in Reviews and Data.

WB Suggested Anti-GJC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate

Host: Rabbit
Target Name: GJC2
Sample Type: MCF7
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: GJC2
Sample Type: 293T
Antibody Dilution: 1.0ug/mlGJC2 is supported by BioGPS gene expression data to be expressed in HEK293T

WB Suggested Anti-GJC2 antibody Titration: 1 ug/mL
Sample Type: Human heart

WB Suggested Anti-GJC2 antibody Titration: 1 ug/mL
Sample Type: Human liver

GJC2 antibody - middle region (ARP36621_P050) in Human MCF-7 using Western Blot