SMARCE1 Antibody - N-terminal region

Product Overview

• Article Name: SMARCE1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP38224_P050
• Supplier Catalog Number: ARP38224_P050
• Alternative Catalog Number: ASB-ARP38224_P050-25UL,ASB-ARP38224_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCE1
• Alternative Names: CSS5, BAF57

Product Description

SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 47kDa
• NCBI: 6605
• UniProt: Q969G3
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

Rabbit Anti-SMARCE1 antibody
Catalog Number: ARP38224
Paraffin Embedded Tissue: Human Lung
cell Cellular Data: alveolar cell
Antibody Concentration: 4.0-8.0 ug/mlMagnification: 400X

Rabbit Anti-SMARCE1 antibody
Catalog Number: ARP38224
Formalin Fixed Paraffin Embedded Tissue: Human Adult Colon
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec

WB Suggested Anti-SMARCE1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateSMARCE1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Lane 1: HeLa (human)Lane 2: NHEM (human)Lane 3: Melba (mouse)Lane 4: NIH3T3 (mouse)Lane 5: S16 (rat)Lane 6: H9C2 (rat)
Primary Antibody Dilution:
1:500
Secondary Antibody:
Donkey anti-rabbit-HRP
Secondary Antibody Dilution:
1:5000
Gene Name:
SMARCE1
Submitted by:
Ivana de la Serna, University of Toledo

SMARCE1 antibody - N-terminal region (ARP38224_P050) in Human Jurkat using Western Blot