KLF4 Antibody - C-terminal region

Product Overview

• Article Name: KLF4 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP38430_P050
• Supplier Catalog Number: ARP38430_P050
• Alternative Catalog Number: ASB-ARP38430_P050-25UL,ASB-ARP38430_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4
• Alternative Names: EZF, GKLF

Product Description

The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 55 kDa
• NCBI: 9314
• UniProt: O43474
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human lung epithelial cell

Human lung cell line

25 ug of the indicated Mouse whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide sequence is contained within isoforms present at 44 kDa and 38 kDa.

prostate

WB Suggested Anti-KLF4 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human heart

Host: Mouse
Target Name: KLF12
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

KLF4 antibody - C-terminal region (ARP38430_P050) in Human lung cell line using Immunohistochemistry