RUNX2 Antibody - N-terminal region

Product Overview

• Article Name: RUNX2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP38452_P050
• Supplier Catalog Number: ARP38452_P050
• Alternative Catalog Number: ASB-ARP38452_P050-25UL,ASB-ARP38452_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RUNX2
• Alternative Names: CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1

Product Description

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 55kDa
• NCBI: 860
• UniProt: Q13950-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-RUNX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateRUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells

Host: Rabbit
Target Name: RUNX2
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: RUNX2
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Sample Type:
Lane 1: 20ug mouse mesenchymal stem cell lysate Primary Antibody Dilution:
1:2000 Secondary Antibody:
Anti-rabbit-HRP Secondary Antibody Dilution:
1:10,000 Color/Signal Descriptions:
RUNX2 Gene Name:
Anonymous Submitted by:

RUNX2 antibody - N-terminal region (ARP38452_P050) in Human 721_B using Western Blot