RCAN1 Antibody - middle region

Catalog Number: ASB-ARP38457_P050
Article Name: RCAN1 Antibody - middle region
Biozol Catalog Number: ASB-ARP38457_P050
Supplier Catalog Number: ARP38457_P050
Alternative Catalog Number: ASB-ARP38457_P050-25UL,ASB-ARP38457_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RCAN1
Alternative Names: CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78
RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 28kDa
NCBI: 1827
UniProt: P53805
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-RCAN1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle
RCAN1 antibody - middle region (ARP38457_P050) validated by WB using Mouse Brain at 1:500.
RCAN1 antibody - middle region (ARP38457_P050) validated by WB using MOUSE OSTEOCLASTS at 1:1000.
WB Suggested Anti-RCAN1 Antibody
Positive Control: Lane 1: 20ug Wild type mouse, left ventricle
Primary Antibody Dilution : 1:1000
Secondary Antibody : Goat anti rabbit-HRP
Secondry Antibody Dilution : 1:5,000
Submitted by: Kathleen Gabrielson
Host: Rabbit
Target Name: RCAN1
Sample Type: Human Fetal Muscle
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1ug/ml
Peptide Concentration: 5ug/ml
Lysate Quantity: 25ug/lane/lane
Gel Concentration: 0.12
Host: Rabbit
Target Name: RCAN1
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml
RCAN1 antibody - middle region (ARP38457_P050) in Human Muscle using Western Blot