ETS2 Antibody - middle region

Product Overview

• Article Name: ETS2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP38592_P050
• Supplier Catalog Number: ARP38592_P050
• Alternative Catalog Number: ASB-ARP38592_P050-25UL,ASB-ARP38592_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ETS2
• Alternative Names: ETS2IT1

Product Description

ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 53kDa
• NCBI: 2114
• UniProt: P15036
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-ETS2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human kidney

ETS2 antibody - middle region (ARP38592_P050) validated by WB using human LCL and mouse brains at 1:1000.

Host: Mouse
Target Name: ETS2
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: ETS2
Positive control (+): Mouse Kidney (M-KI)
Negative control (-): Mouse Testis (M-TE)
Antibody concentration: 1ug/ml

ETS2 antibody - middle region (ARP38592_P050) in Human kidney using Western Blot