STAT1 Antibody - N-terminal region

Product Overview

• Article Name: STAT1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP38933_P050
• Supplier Catalog Number: ARP38933_P050
• Alternative Catalog Number: ASB-ARP38933_P050-25UL,ASB-ARP38933_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1
• Alternative Names: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91

Product Description

STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 87 kDa
• NCBI: 6772
• UniProt: P42224
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Immunohistochemistry with Pancreas tissue at an antibody concentration of 5.0ug/ml using anti-STAT1 antibody (ARP38933_P050)

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Protein is modified by phosphorylation and methylation.

Rabbit Anti-STAT1 Antibody
Catalog Number: ARP38933
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-STAT1 Antibody Titration: 1 ug/ml
Positive Control: STAT1

Host: Mouse
Target Name: STAT1
Sample Tissue: Mouse Pancreas
Antibody Dilution: 1ug/ml

STAT1 antibody - N-terminal region (ARP38933_P050) in r-STAT1 using Western Blot