TARDBP Antibody - N-terminal region

Catalog Number: ASB-ARP38941_T100
Article Name: TARDBP Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP38941_T100
Supplier Catalog Number: ARP38941_T100
Alternative Catalog Number: ASB-ARP38941_T100-25UL,ASB-ARP38941_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TARDBP
Alternative Names: ALS10, TDP-43
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 45kDa
NCBI: 23435
UniProt: Q13148
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
Human Liver
WB Suggested Anti-TARDBP Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysateTARDBP is supported by BioGPS gene expression data to be expressed in HepG2
Host: Rabbit
Target Name: TARDBP
Sample Type: HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1.25ug/mL
Peptide Concentration: 1.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12%TARDBP is supported by BioGPS gene expression data to be expressed in HepG2
25 ug of the indicated whole cell extracts was loaded onto a 12% SDS-PAGE gel. 5 ug/mL of the antibody was used in this experiment. Recommended dilution for antibody is 1-3 ug/mL. Two or more isoforms of this protein are known and at least two share the N-terminal peptide sequence.
TARDBP antibody - N-terminal region (ARP38941_T100) in HepG2 using Western Blot