NFYC Antibody - C-terminal region

Product Overview

• Article Name: NFYC Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP39066_P050
• Supplier Catalog Number: ARP39066_P050
• Alternative Catalog Number: ASB-ARP39066_P050-25UL,ASB-ARP39066_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC
• Alternative Names: HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A

Product Description

NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 37kDa
• NCBI: 4802
• UniProt: Q13952
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Liver

WB Suggested Anti-NFYC Antibody Titration: 0.25 ug/ml
Positive Control: 293T cells lysateThere is BioGPS gene expression data showing that NFYC is expressed in HEK293T

Host: Mouse
Target Name: NFYC
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml

NFYC antibody - C-terminal region (ARP39066_P050) in Human 293T using Western Blot