DEAF1 Antibody - N-terminal region

Product Overview

• Article Name: DEAF1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP39467_P050
• Supplier Catalog Number: ARP39467_P050
• Alternative Catalog Number: ASB-ARP39467_P050-25UL,ASB-ARP39467_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Rat, Yeast
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DEAF1
• Alternative Names: SPN, NUDR, VSVS, MRD24, ZMYND5, NEDHELS

Product Description

DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 59kDa
• NCBI: 10522
• UniProt: O75398
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-DEAF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human brain

Hum. Fetal Lung

Hum. Fetal Muscle

Hum. Adult Placenta

DEAF1 antibody - N-terminal region (ARP39467_P050) in Human Brain using Western Blot