FUS Antibody - N-terminal region

Product Overview

• Article Name: FUS Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP40278_P050
• Supplier Catalog Number: ARP40278_P050
• Alternative Catalog Number: ASB-ARP40278_P050-25UL,ASB-ARP40278_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUS
• Alternative Names: TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2

Product Description

FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 53 kDa
• NCBI: 2521
• UniProt: P35637
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-FUS Antibody
Catalog Number: ARP40278
Paraffin Embedded Tissue: Human Intestine
Cellular Data: Epithelial cells of intestinal villas
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Rabbit Anti-FUS Antibody
Catalog Number: ARP40278
Paraffin Embedded Tissue: Human Breast
Antibody Concentration: 5 ug/ml

Rabbit Anti-FUS Antibody
Catalog Number: ARP40278
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-FUS Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateFUS is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells

WB Suggested Anti-FUS Antibody
Positive Control: Lane 1: 5ug mouse brain cytoplasm Lane 2: 5ug mouse brain nucleus
Primary Antibody Dilution : 1:1000
Secondary Antibody : Anti rabbit - IR-dye
Secondry Antibody Dilution : 1:10,000
Submitted by: Anonymous

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. 53 kDa protein has extensive modification of arginines and contains a SUMO2 site.

Host: Rabbit
Target Name: FUS
Sample Type: Lane 1: Human MCF-7 cell lysateK562
Lane 2: Human THP-1 cell lysate
Lane 3: Human Hela cell lysate
Antibody Dilution: 1.0ug/ml

FUS antibody - N-terminal region (ARP40278_P050) in mouse brain using Western Blot