YARS Antibody - C-terminal region, Rabbit, Polyclonal

Catalog Number: ASB-ARP40471_T100
Article Name: YARS Antibody - C-terminal region, Rabbit, Polyclonal
Biozol Catalog Number: ASB-ARP40471_T100
Supplier Catalog Number: ARP40471_T100
Alternative Catalog Number: ASB-ARP40471_T100-25UL,ASB-ARP40471_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human YARS
Alternative Names: YRS, YTS, YARS, TYRRS, CMTDIC
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 58kDa
NCBI: 8565
UniProt: P54577
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.