IREB2 Antibody - middle region, Rabbit, Polyclonal

Product Overview

• Article Name: IREB2 Antibody - middle region, Rabbit, Polyclonal
• Biozol Catalog Number: ASB-ARP40509_P050
• Supplier Catalog Number: ARP40509_P050
• Alternative Catalog Number: ASB-ARP40509_P050-25UL,ASB-ARP40509_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IREB2
• Alternative Names: ACO3, IRP2, IRP2AD, NDCAMA, IRE-BP2, IRE-BP 2

Product Description

IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 105kDa
• NCBI: 3658
• UniProt: P48200
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.