IREB2 Antibody - middle region

Product Overview

• Article Name: IREB2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP40509_P050
• Supplier Catalog Number: ARP40509_P050
• Alternative Catalog Number: ASB-ARP40509_P050-25UL,ASB-ARP40509_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IREB2
• Alternative Names: ACO3, IRP2, IRP2AD, NDCAMA, IRE-BP2, IRE-BP 2

Product Description

IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 105kDa
• NCBI: 3658
• UniProt: P48200
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-IREB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Liver

Researcher: Dr. Hao Zhu, University of Kansas Medical Center
Application: Western blotting
Species+tissue/cell type: Mouse liver extract
How many ugsof tissue/cell lysate run on the gel:1. 60 ug mouse liver extract2. 60 ug mouse liver extract3. 60 ug mouse liver extract
Primary antibody dilution: 1:500
Secondary antibody: Anti-rabbit HRP
Secondary antibody dilution: 1:3000

Host: Rabbit
Target Name: IREB2
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

IREB2 antibody - middle region (ARP40509_P050) in Mouse Liver using Western Blot