PUF60 Antibody - C-terminal region

Article Name:	PUF60 Antibody - C-terminal region
Biozol Catalog Number:	ASB-ARP40760_P050
Supplier Catalog Number:	ARP40760_P050
Alternative Catalog Number:	ASB-ARP40760_P050-25UL,ASB-ARP40760_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	IHC, WB
Species Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen:	The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60
Alternative Names:	FIR, VRJS, RoBPI, SIAHBP1

PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	58kDa
NCBI:	22827
UniProt:	Q9UHX1-2
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.


	Rabbit Anti-PUF60 Antibody Catalog Number: ARP40760 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X
	WB Suggested Anti-PUF60 Antibody Titration: 0.5ug/ml Positive Control: Human 293T Cell Lysate
	Rabbit Anti-PUF60 antibody Catalog Number: ARP40760 Formalin Fixed Paraffin Embedded Tissue: Human Colon Primary antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20x Exposure Time: 0.5-2.0sec
	WB Suggested Anti-PUF60 Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cell lysatePUF60 is supported by BioGPS gene expression data to be expressed in HeLa
	Host: Rabbit Target Name: PUF60 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml
	Host: Rabbit Target Name: PUF60 Sample Type: Human Fetal Lung Antibody Dilution: 1.0ug/ml
	PUF60 antibody - C-terminal region (ARP40760_P050) in Human 293T using Western Blot