PUF60 Antibody - C-terminal region

Product Overview

• Article Name: PUF60 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP40760_T100
• Supplier Catalog Number: ARP40760_T100
• Alternative Catalog Number: ASB-ARP40760_T100-25UL,ASB-ARP40760_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60
• Alternative Names: FIR, VRJS, RoBPI, SIAHBP1

Product Description

PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 58kDa
• NCBI: 22827
• UniProt: Q9UHX1-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

ARP40760_T100

Rabbit Anti-PUF60 Antibody Catalog Number: ARP40760 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X

WB Suggested Anti-PUF60 Antibody
Titration: 0.5ug/ml
Positive Control: Human 293T Cell Lysate

WB Suggested Anti-PUF60 Antibody Titration: 0.2-1 ug/mlPositive Control: HelaPUF60 is supported by BioGPS gene expression data to be expressed in HeLa

PUF60 antibody - C-terminal region (ARP40760_T100) in Human 293T using Western Blot