MSLN Antibody - middle region

Product Overview

• Article Name: MSLN Antibody - middle region
• Biozol Catalog Number: ASB-ARP42262_P050
• Supplier Catalog Number: ARP42262_P050
• Alternative Catalog Number: ASB-ARP42262_P050-25UL,ASB-ARP42262_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MSLN
• Alternative Names: MPF, SMRP

Product Description

An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin.An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 69 kDa
• NCBI: 10232
• UniProt: Q13421-3
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-MSLN Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate

Host: Mouse
Target Name: MSLN
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: MSLN
Positive control (+): Hela (HL)
Negative control (-): Human liver (LI)
Antibody concentration: 3ug/ml

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

MSLN antibody - middle region (ARP42262_P050) in Human MCF-7 using Western Blot