RHCE Antibody - N-terminal region
Catalog Number:
ASB-ARP42567_P050
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| Article Name: | RHCE Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP42567_P050 |
| Supplier Catalog Number: | ARP42567_P050 |
| Alternative Catalog Number: | ASB-ARP42567_P050-25UL,ASB-ARP42567_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RHCE |
| Alternative Names: | RH, RHC, RHE, Rh4, RHNA, RHPI, RhVI, RH30A, RHIXB, RhVIII, CD240CE, RhIVb(J), RHCe(152N) |
| The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease.The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. |
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