FBXW2 Antibody - middle region

Article Name:	FBXW2 Antibody - middle region
Biozol Catalog Number:	ASB-ARP43109_P050
Supplier Catalog Number:	ARP43109_P050
Alternative Catalog Number:	ASB-ARP43109_P050-25UL,ASB-ARP43109_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	WB
Species Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:	The immunogen is a synthetic peptide directed towards the middle region of human FBXW2
Alternative Names:	Md6, FBW2, Fwd2

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	51kDa
NCBI:	26190
UniProt:	Q9UKT8
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	WB Suggested Anti-FBXW2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysateFBXW2 is supported by BioGPS gene expression data to be expressed in Jurkat
	Host: Rabbit Target Name: CHAD Sample Type: Human Adult Placenta Antibody Dilution: 1.0ug/ml
	Host: Rabbit Target Name: FBXW2 Sample Type: Human Fetal Heart Antibody Dilution: 1.0ug/ml
	Host: Rabbit Target Name: FBXW2 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml
	Host: Rabbit Target Name: FBXW2 Sample Type: Human Fetal Lung Antibody Dilution: 1.0ug/ml
	Host: Rabbit Target: FBXW2 Positive control (+): Human Placenta (PL) Negative control (-): 293T Cell Lysate (2T) Antibody concentration: 1ug/ml
	FBXW2 antibody - middle region (ARP43109_P050) in Human Jurkat using Western Blot