CREBBP Antibody - N-terminal region

Product Overview

• Article Name: CREBBP Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP43609_P050
• Supplier Catalog Number: ARP43609_P050
• Alternative Catalog Number: ASB-ARP43609_P050-25UL,ASB-ARP43609_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREBBP
• Alternative Names: CBP, RSTS, KAT3A, MKHK1, RSTS1

Product Description

CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 261kDa
• NCBI: 1387
• UniProt: Q4LE28
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Anti-CREBBP antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Anti-CREBBP Antibody
Catalog Number: arp43609
Paraffin Embedded Tissue: Human Colon
Antibody Concentration: 5 ug/ml

WB Suggested Anti-CREBBP Antibody Titration: 1 ug/ml
Positive Control: Jurkat cell lysate

Host: Rabbit
Target: CREBBP
Positive control (+): Human Lung Tumor (T-LU)
Negative control (-): Human Liver Tumor (T-LI)
Antibody concentration: 0.25ug/ml

CREBBP antibody - N-terminal region (ARP43609_P050) in Human Jurkat using Western Blot