GGCX Antibody - middle region

Product Overview

• Article Name: GGCX Antibody - middle region
• Biozol Catalog Number: ASB-ARP44340_P050
• Supplier Catalog Number: ARP44340_P050
• Alternative Catalog Number: ASB-ARP44340_P050-25UL,ASB-ARP44340_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GGCX
• Alternative Names: VKCFD1

Product Description

GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 87kDa
• NCBI: 2677
• UniProt: P38435
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-GGCX Antibody
Catalog Number: ARP44340_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver
Observed Staining: Cytoplasm in hepatocytes, strong signal, wide tissue distribution
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Protocol located in Reviews and Data.

WB Suggested Anti-GGCX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysate.GGCX is strongly supported by BioGPS gene expression data to be expressed in MCF7

Host: Rabbit
Target Name: GGCX
Sample Type: Jurkat
Antibody Dilution: 1.0ug/mlGGCX is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Host: Rabbit
Target Name: GGCX
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

GGCX antibody - middle region (ARP44340_P050) in Human MCF-7 using Western Blot