GPNMB Antibody - N-terminal region

Product Overview

• Article Name: GPNMB Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP44499_P050
• Supplier Catalog Number: ARP44499_P050
• Alternative Catalog Number: ASB-ARP44499_P050-25UL,ASB-ARP44499_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
• Alternative Names: NMB, HGFIN, PLCA3

Product Description

GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 63 kDa
• NCBI: 10457
• UniProt: Q14956
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Lung

WB Suggested Anti-GPNMB Antibody Titration: 1 ug/ml
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: GPNMB
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: GPNMB
Sample Tissue: Human Hela Whole Cell
Antibody Dilution: 1ug/ml

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for antibody is 1-3 ug/mL

GPNMB antibody - N-terminal region (ARP44499_P050) in Human Fetal Lung using Western Blot