PARL Antibody - N-terminal region

Product Overview

• Article Name: PARL Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP44851_P050
• Supplier Catalog Number: ARP44851_P050
• Alternative Catalog Number: ASB-ARP44851_P050-25UL,ASB-ARP44851_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PARL
• Alternative Names: PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2

Product Description

PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 36kDa
• NCBI: 55486
• UniProt: Q9H300-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

Rabbit Anti-PARL Antibody
Catalog Number: ARP44851_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasmic in alveolar type I cells
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-PARL Antibody Titration: 0.5ug/ml
Positive Control: Jurkat cell lysatePARL is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: PARL
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml

PARL antibody - N-terminal region (ARP44851_P050) in Human Jurkat using Western Blot