PCDHGC3 Antibody - C-terminal region
Catalog Number:
ASB-ARP45336_P050
- Images (4)
| Article Name: | PCDHGC3 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP45336_P050 |
| Supplier Catalog Number: | ARP45336_P050 |
| Alternative Catalog Number: | ASB-ARP45336_P050-25UL,ASB-ARP45336_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHGC3 |
| Alternative Names: | PC43, PCDH2, PCDH-GAMMA-C3 |
| This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
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WB Suggested Anti-PCDHGC3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysateThere is BioGPS gene expression data showing that PCDHGC3 is expressed in 721_B |
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Host: Rabbit Target Name: CHAD Sample Type: Human Adult Placenta Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: PCDHGC3 Sample Type: 293T Antibody Dilution: 1.0ug/ml |
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PCDHGC3 antibody - C-terminal region (ARP45336_P050) in Human 721_B using Western Blot |
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