TFR2 Antibody - N-terminal region

Product Overview

• Article Name: TFR2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP45441_P050
• Supplier Catalog Number: ARP45441_P050
• Alternative Catalog Number: ASB-ARP45441_P050-25UL,ASB-ARP45441_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFR2
• Alternative Names: HFE3, TFRC2

Product Description

TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 89kDa
• NCBI: 7036
• UniProt: Q9UP52
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Skin

WB Suggested Anti-TFR2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

Host: Rabbit
Target: TFR2
Positive control (+): HepG2 Cell Lysate (HG)
Negative control (-): 293T Cell Lysate (2T)
Antibody concentration: 5ug/ml

TFR2 antibody - N-terminal region (ARP45441_P050) in Human Muscle using Western Blot