GLUD1 Antibody - N-terminal region

Product Overview

• Article Name: GLUD1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP45708_P050
• Supplier Catalog Number: ARP45708_P050
• Alternative Catalog Number: ASB-ARP45708_P050-25UL,ASB-ARP45708_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rat, Sheep, Yeast, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLUD1
• Alternative Names: GDH, GDH1, GLUD

Product Description

L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification. L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 56kDa
• NCBI: 2746
• UniProt: P00367
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Immunohistochemistry with PFA fixed human colon tissue tissue

Immunohistochemistry with CORTEX/KIDNEY tissue

Immunohistochemistry with pFA fixed human pancreas tissue tissue

GLUD1 antibody - N-terminal region (ARP45708_P050) validated by WB using HT1080 cell lysate at 1ug/ml.GLUD1 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells

lanes 5: rat kidney cordex
lanes 6: rat kidney proximal tubules prepped from cortex
lanes 7: LLCPK-F+ pig kidney proximal tubule tissue culture lysate
lanes 8: rat brain supernatant

GLUD1 antibody - N-terminal region (ARP45708_P050) in Human HT1080 using Western Blot