TDO2 Antibody - N-terminal region

Product Overview

• Article Name: TDO2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP45716_P050
• Supplier Catalog Number: ARP45716_P050
• Alternative Catalog Number: ASB-ARP45716_P050-25UL,ASB-ARP45716_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Canine, Human, Porcine
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TDO2
• Alternative Names: TO, TDO, TPH2, TRPO, HYPTRP

Product Description

Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 48kDa
• NCBI: 6999
• UniProt: P48775
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Anti-TDO2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ARP45716_P050 concentration 5 ug/ml.

WB Suggested Anti-TDO2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Fetal Heart

Rabbit Anti-CDH8 Antibody
Catalog Number: ARP45716
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Host: Rabbit
Target Name: TDO2
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: TDO2
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 5ug/ml

Host: Rabbit
Target Name: TDO2
Sample Tissue: Human 293T Whole Cell
Antibody Dilution: 1ug/ml

Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown.

TDO2 antibody - N-terminal region (ARP45716_P050) in Human Fetal Heart using Western Blot