SOD1 Antibody - N-terminal region

Product Overview

• Article Name: SOD1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP45752_T100
• Supplier Catalog Number: ARP45752_T100
• Alternative Catalog Number: ASB-ARP45752_T100-25UL,ASB-ARP45752_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOD1
• Alternative Names: ALS, SOD, ALS1, IPOA, STAHP, hSod1, HEL-S-44, homodimer

Product Description

SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 16kDa
• NCBI: 6647
• UniProt: P00441
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

WB Suggested Antibody Titration: 2.5 ug/ml
Positive Control: JurkatSOD1 is supported by BioGPS gene expression data to be expressed in Jurkat

Lanes:
Lane 1: 50ug HeLa lysate
Lane 2: 50ug 293T lysate
Lane 3: 50ug K562 lysate
Lane 4: 50ug MDA-MB-231 lysate
Primary Antibody Dilution:
1:500
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Gene Name:
SOD1
Submitted by:
David Colecchia, Ph.D, Istituto Toscano Tumori, Core Research Laboratory, presso Fondazione Toscana Life Sciences

SOD1 antibody - N-terminal region (ARP45752_T100) in Human Jurkat using Western Blot