CTH Antibody - N-terminal region

Product Overview

• Article Name: CTH Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP46067_P050
• Supplier Catalog Number: ARP46067_P050
• Alternative Catalog Number: ASB-ARP46067_P050-25UL,ASB-ARP46067_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTH
• Alternative Names: MGC9471

Product Description

CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 45 kDa
• NCBI: 1491
• UniProt: P32929
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-CTH Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Host: Rabbit
Target Name: CTH
Sample Type: Human K562 cell lysate
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target: CTH
Positive control (+): Human liver (LI)
Negative control (-): 293T (2T)
Antibody concentration: 3ug/ml

Host: Rabbit
Target Name: CTH
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: CTH
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 1ug/ml

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3ug/mL of the antibody was used in this experiment. The peptide is present in isoforms of 45 kDa, 41 kDa and 39 kDa.

Host: Rabbit
Target Name: CTH
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 3ug/ml

CTH antibody - N-terminal region (ARP46067_P050) in K562 using Western Blot