MMP7 Antibody - C-terminal region, Rabbit, Polyclonal
Catalog Number:
ASB-ARP46075_T100
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| Article Name: | MMP7 Antibody - C-terminal region, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-ARP46075_T100 |
| Supplier Catalog Number: | ARP46075_T100 |
| Alternative Catalog Number: | ASB-ARP46075_T100-25UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Guinea pig, Human, Rabbit, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human MMP7 |
| Alternative Names: | MMP-7, MPSL1, PUMP-1 |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
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