SILV Antibody - N-terminal region

Product Overview

• Article Name: SILV Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP46802_T100
• Supplier Catalog Number: ARP46802_T100
• Alternative Catalog Number: ASB-ARP46802_T100-25UL,ASB-ARP46802_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, IP, WB
• Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SILV
• Alternative Names: P1, SI, SIL, ME20, P100, SILV, ME20M, gp100, ME20-M, PMEL17, D12S53E

Product Description

SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 70kDa
• NCBI: 6490
• UniProt: P40967
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

PMEL was immunoprecipitated from 1 mg HEK293 Whole Cell Lysate with ARP46802_T100 with 1:200 dilution. Western blot was performed using ARP46802_T100 at 1/1000 dilution.
Lane 1: Control IP in HEK293 Whole Cell Lysate.
Lane 2: PMEL IP with ARP46802_T100 in HEK293 Whole Cell Lysate.
Lane 3: Input of HEK293 Whole Cell Lysate.

WB Suggested Anti-SILV Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: SILV
Sample Tissue: Human MCF7
Antibody Dilution: 1.0ug/ml

SILV antibody - N-terminal region (ARP46802_T100) in Human MCF7 using Western Blot