PCDH12 Antibody - middle region, Rabbit, Polyclonal
Catalog Number:
ASB-ARP47275_P050
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| Article Name: | PCDH12 Antibody - middle region, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-ARP47275_P050 |
| Supplier Catalog Number: | ARP47275_P050 |
| Alternative Catalog Number: | ASB-ARP47275_P050-25UL,ASB-ARP47275_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human PCDH12 |
| Alternative Names: | DMJDS1, VECAD2, VE-cadherin-2 |
| PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. |
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